Tree of Life Tree of Life Retinol Serum with Hyaluronic Acid, 2 Fl Oz product photo
Tree of Life

Tree of Life Retinol Serum with Hyaluronic Acid, 2 Fl Oz

4.4 · 143k reviews
$9.99approx.
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What it is

Tree of Life's Retinol Serum pairs a low-to-moderate concentration of retinol with hyaluronic acid in a lightweight, water-based formula designed for everyday use. The combination targets the two most common early-aging complaints — surface texture and loss of moisture — without requiring a prescription. At 2 fl oz, it delivers a solid supply for consistent, multi-week use.

Who it's for

This serum suits normal, oily, combination, and mildly dry skin types that are new to retinol or returning after a break. It works well for adults beginning to address fine lines, uneven tone, or persistent dull patches. The hyaluronic acid component makes it more forgiving than pure retinol serums, so sensitive skin types can often tolerate it if they start slowly — two to three nights per week at first.

Who should skip it: Those currently using prescription retinoids, exfoliating acids (AHAs, BHAs) nightly, or benzoyl peroxide should not layer this on top without spacing treatments out. Anyone who is pregnant or nursing should consult a healthcare provider before using any retinol product.

How to use it

Apply to clean, completely dry skin at night — retinol degrades in sunlight and works best when skin is not damp, which can amplify irritation. Dispense three to four drops, press gently across the face and neck, and let absorb for sixty seconds before following with a moisturizer. Beginners should start two nights per week for the first three to four weeks, then increase to every other night and eventually nightly as tolerance builds. Always apply a broad-spectrum SPF 30 or higher the following morning; retinol accelerates cell turnover, leaving fresh skin temporarily more UV-sensitive.

Key ingredients

Retinol is a vitamin A derivative that signals skin cells to turn over faster, gradually reducing the appearance of fine lines, smoothing texture, and fading post-inflammatory marks over weeks of consistent use. It does not produce overnight results — expect a realistic timeline of six to twelve weeks before visible improvement in fine lines, and four to eight weeks for initial tone improvement.

Hyaluronic acid is a humectant that draws water from the environment and deeper skin layers toward the surface, plumping the appearance of dehydration lines and helping to counterbalance the temporary dryness retinol can cause, especially during the adjustment period.

Pros & cons

  • Accessible entry point for retinol — the formulation is gentler than prescription-strength options, making the adjustment period more manageable
  • Dual-action on two major concerns — retinol addresses texture and fine lines while hyaluronic acid supports hydration simultaneously
  • Well-reviewed at scale — 4.4 out of 5 stars across more than 143,000 reviews signals broad, real-world satisfaction
  • Lightweight texture — absorbs without a greasy or heavy finish, compatible with most moisturizers and sunscreens
  • Retinol concentration is not disclosed — without knowing the exact percentage, it's difficult to compare potency to other serums or to escalate your routine methodically
  • Not suitable for daytime use — retinol requires a strict nighttime-only application, which adds a step to morning SPF diligence
  • Purging is possible — some users experience a temporary increase in breakouts or flaking in the first two to four weeks as cell turnover accelerates
  • Not fragrance-free — formulary details vary; those with fragrance sensitivity should check the current ingredient list before purchasing

How it compares

If brightening and hyperpigmentation are your primary goals rather than anti-aging texture, the TruSkin Vitamin C Serum with Hyaluronic Acid & Vitamin E is worth considering alongside this serum — vitamin C addresses oxidative dullness and dark spots through a different mechanism than retinol, and the two can be alternated (morning vs. night) for a more comprehensive routine.

If you want deeper hydration without introducing retinol at all, Tree of Life's own Hyaluronic Acid Serum for Face isolates the humectant step and is appropriate for every skin type, including those who are pregnant or retinol-sensitive.

The verdict

Tree of Life's Retinol Serum is a practical, low-barrier starting point for anyone who wants to incorporate retinol into their routine without committing to a high-potency formula right away. The addition of hyaluronic acid takes some of the edge off the typical adjustment period, and the volume of positive real-world reviews across a very large sample suggests it performs reliably for a wide range of skin types. The main limitation is the lack of disclosed retinol concentration, which makes it harder to build a progressive retinol regimen over time. For early-stage fine lines, minor dark spots, and general maintenance, it earns its place in a consistent nighttime routine — provided you commit to daily SPF.

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What shoppers say

★ 4.4average from 143k ratings on Amazon

Fans consistently praise the featherlight texture that sinks in fast without greasiness or residue. With regular nightly use, many report visibly smoother skin, improved firmness, and a more even tone — including reduced redness for some sensitive-skin users.

The main caveat is patience: reviewers who've worked in healthcare caution there are no quick fixes, and meaningful results seem to require weeks of consistent use. Those expecting rapid transformation may be disappointed. No notable complaints about irritation appeared, but new retinol users should still start slowly.

★★★★★ AMP Verified purchase Aug 8, 2020
YES, MA’AM! YOU NEED THESE SERUMS, LADIES!

Okay - I do not leave reviews unless I honestly love a product/products, and I know it can be hard to know (on Amazon) these days who’s a REAL customer & who isn’t. I’m real, folks! I paid full price and received nothing for free, so please hear what I’m saying about these products. We are in the fight for beautiful, younger, fresher skin together! I bought these 3 serums and have used them for the past week (since receiving my shipment quickly...within 24 hrs) and WOW! When my husband said,”Oh my God! No joke babe, your skin looks younger - YOU look younger...” and he was right! Usually would take weeks to see a difference, but let me tell you, this was immediate. I also purchased a derma roller to use with the serums a few days a week. I’ll explain below! I’m about to turn 43 years old & my skin has/had become “ruddy”, red, splotchy, uneven texture, some hyper-pigmentation (i.e. age spots) with dry patches and then a super-oily t-zone - ahhhhhh!! Then, there are the lovely fine lines & wrinkles that were developing around my mouth, forehead, and between brows as well. If you’re over 40, you know what I’m saying.. Okay, so I also bought a derma roller to use as well. I also use Zinc bar soap for my daily face wash - and I had been out of my Zinc soap for a couple of months, which is no bueno for my skin. Zinc soap is great for redness, rosacea, flakiness around nose and eyebrows (which you may think is dry skin, but it’s actually flakes produced from excessive oil in those areas....so it helps that PLUS helps with my redness in other areas on my face, AND doesn’t dry my skin out...so I highly recommend a Zinc soap if any of you gals are dealing with what looks like dry flakes in/around eyebrows and nose! Get the Zinc soap! It’s about $8-$10 on Amazon). So, in the a.m., day #1, washed with Zinc Soap, rinsed with warm water (not hot), then got my derma roller out (it has tiny little needles on it, so NOT the jade roller, but a derma roller- WITH needles), washed it with rubbing alcohol first to sterilize, then held my skin taught and rolled up & down my face vertically (whole face...lips too - and make a face to stretch your lips taught, otherwise it won’t work on the lips 👄), then went back over my entire face horizontally (I watched several videos on how to safely use the derma roller, so please watch some videos so that you don’t overdo it), my face was a little red, but it did not hurt at all. It creates tiny little “holes” (or little “traumas” if you will) that your body will send collagen to fix, thus forcing collagen into those areas to repair and rejuvenate- GENIUS! So, THEN you go and put those 3 serums on right over the freshly derma rolled skin, and BOOM! My skin LITERALLY plumped up before my eyes! I put vitamin C on first, then use the cool setting on my blowdryer to blow it dry a bit, then I do the retinol serum, then cool dry a bit to allow it to absorb, then I put the last serum on after that and let it sink in. That evening I washed my face with Zinc soap before bed and then use Tree Of Life Moisturizer Cream with retinol and hyarulonic acid afterward and sleep with that stuff on. A little goes a long way with Tree of Life serums and mousturizers too, so don’t feel like you have to slather it on. You don’t! I put my makeup on right over the top of the serums (I wait about 30 min before applying makeup, just to allow the serums to soak in. I allow 1 to 2 days between derma rolling, and just do my zinc soap for face wash and then I apply the serums as usual, without the derma roller on the “in-between-derma-rolling-days”. My fine lines are definitely less noticeable and the places with hyper pigmentation have faded out quite a bit (not entirely- but dude, it’s been literally like 6 days...so IMAGINE what my skin will look like in a month?!). Also, my skin texture is absolutely smoother and the color is SO much more even already. Let me be clear though, my skin is totally red after I apply the serums...and then it calms. It doesn’t hurt whatsoever, but initially I am red right after applying. Especially after derma rolling and applying - expect immediate redness and then it will go away. I’ve used a lot of serums, and these 3 are the best I’ve found! Purchase them! Be diligent and apply daily - there is NO WAY that you aren’t going to see improvement in your skin! Younger, softer, smoother skin is here. Awesome job, Tree of Life!

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★★★★ MichelleA Verified purchase Oct 26, 2018
Excellent Line- Excellent Price.

I often tend to only give 1-4 stars with new products because having been in healthcare for 17 years, I KNOW there is NO miracle overnight-Fix! So it’s important (at least to me) to always be honest. That said, when I read reviews myself, I often zoom in on the “unsatisfied” reviews- 1st. —Why? Because 8/10 times the comments are based on “Immediate reactions.” We must remember that our “SKIN” is the largest organ in our body. It has a TON of responsibilities. So we must “Help” by not just “Topical” care, but equally important- Start within. (My rule of thumb is think of our Skin exactly like a Garden of Planted Flowers. What’s first? Yes, Water.. Nutrients.. the better we continue caring (watering/feeding) our Flowers... the better they Bloom! Skin is NO DIFFERENT. Even if a Flower blossoms overnight (rare, but “it happens) we still need to care for it in order for it to remain beautiful. I’m VERY picky when it comes to my Skin. I’m turning 47 next week, Mom of 3 (and a Grandma:) I still recall childhood of my sneaking into my Mom’s Med Cabinet to find the (most notorious “Oil of Olay.” Point: I started young. I found TOLB a couple years ago. I had Stopped for a bit (convincing myself of the hype over Designer labels) on skincare. (If a Par of jeans look fabulous on us— Do we REALLY care of the label or cost?) I don’t! I often then look at the other 50 pairs of $100+ Jeans in my closet and think I’m an idiot. So let’s go back to the Garden.. a LOT of factors go in too gorgeous field of Flowers. We can/better, water it daily but what else is mandatory? Yep, Sunliigt (Vit C) and of course nutrition. I won’t lie, I am A Product Junkie (I suppose I could be addicted to worse..) I saw Comments here of certain products being “Watery” or “its not a serum” and so on— It’s simply NOT TRUE. (Can you imagine layering 5 Thick serums + Moisturizing + SPF? 😳 yeah, me either! I’m a HUGE fan of the fact Vit C is one of our most liquified serums. (Kind of like an Essence is, we should “PRESS IT INTO OUR SKIN” not rub. (I presume we all follow the staple rule of “Thin to Thick” when we later products?) so TOLB is an EXCELLENT product in my opinion. Having stopped once, then resuming (that’s how we often realize “challenge/error” (why did I stop NHM HMM!) At least that’s how I built My Arsenal of skin care. TOLB has stood the test against my $100 labels (which need I explain “Marketing?”) They’re on TV, Famous people are the spokesmodels, etc) so it MUST work— WRONG! Don’t get me wrong, My bathroom has its own closet sized Dept. Store of those products) I often assumed “More expensive- it has to work) mantra. (Staring at a covergirl using a designer “magic serum” — yeah, I got Fooled too!) Again, simply NOT true. And Tryst me, Im the “go to girl” with my friends for my “new finds” always looking for the next new product that actually works— TOLB is one line I can support by my own proven comparisons) I’m “THAT Girl” who lines hers up (Day/Night) and seldom skip a beat. I look Forward to caring for my facial skin (it IS often the 1st thing we see when we look at another. - We don’t talk to their knees!) so why not make it a Priority? Now, “My Routine” is not for the faint of heart :) after my showers - while I’m getting ready is how I begin My layering. (Most often during hair products, blow drying, etc) so there is NO RUSH and each have time to “Do their Job!” I’ll share my arsenal but it’s only because TOLB is so far the only line that most all can afford. (Exfoliating is my last step in my shower.) I keep My jar of daily exfoliant and my Large pump bottle of Coconut oil in my shower) I exfoliate my body there, so why not my face? This way, once out and dried.. the “Stage” is set. I begin: (Face wash, Tone - Anyone who does not TONE - do it now!) such an easy swipe of quick drying - pallet preparing greatness. (Seriously, stop reading, go Tone!) I don’t know about you but I’m not wasting products on a old skin cell canvas, are you? (Preparing the soil- Water, Raking, etc) Next (my Absolute Must) “ESSENCE.” Yeah, she’s not that new.. but more often than not she’s forgotten. Essence is the Gardener. She’s in charge! Without Essence (Pressing into skin/Do NOT RUB and DO NOT WASTE ON COTTON PAD) Infact, the ONLY Colton pad Swipe you should ever use is Toner. Otherwise, no explanation needed- Wasteful! So while I’m preparing my hair for blow dry (yes, there are layering products in hair regimen too) my skin is drinking up.. while sitting in the Sunshine (Vit C that has been pressed into my face.) Rookies: (smile) Place few drops in one palm and use 2 fingers opposite hand and dip/dab into all regions of your face (check/chin/forehead etc) then go back and LIGHTLY spread) now using 2 fingers of each hand, gently pressing into face. I end By a little extra TLC on any bullies on my playground (age/sun spots) they gotta go! Now it’s time for my Treatment serums. These most likely are now becoming “serum like” why? - They have a bigger responsibility. Another Absolute MUST is choosing a serum or Serum (S) that Target the needs we feel are our most bothersome. (We’re all different!) but I don’t agree, just my opinion) with time of year- change my routine) Even if I’m not physically tending to my flowerbed.. Mother Nature is— (so she doesn’t have time to do my job!) For me, I have a few serums. I start with Peptides (vitamins) then age prevention! (Your choice) — then once I’m done blow drying (Or styling if not a blow dry day) That’s plenty of time for all the team to have completed their job. But Nope- I’m not done. -Next, HA. Think of HA as a “LOCK” (in the “Lock & Load) HA is really just a Serum Moisturizer. (Supervisor in the Garden) Once she’s on Duty. The rest can go. She’ll report too— The Manager (Moisturizer & SPF!) I dont use separately UNLESS I’m going to be out and about all day (Yes, we need SPF regardless if Sunny) I just use a “Transformation Moisture Day Cream” that INCLUDES SPF- nothing less than 15-20!) but if I’m actual Sunlight nothing less than 30+ and THAT will be a 2nd layer OVER my TMDC! (Now is it more understandable that all serums/treatments have different textures?) One step I didnt add.. I’m the lucky one who fights Cystic Acne in my 40’s (I agree, what the heck?!) THOSE DARN PESTS! So if Bad, I treat At Night & Spot Treat (AFTER VIT C!) But Night Regime (esp Retinol & AH take charge.) But if I even Look At a Jellybean- Boom!) and that Stinks because they’re my Weakness (oh and Cheese grrrr) But I’m not about to give up either (a girl needs a little fun!) so my skin care just has more work to do at times. —- So once all of the garden is Prepped for the day— if makeup (I myself believe in a Kabuki/Mineral (non liquid) application) I think The only “soft liquid” I apply in regards to makeup is Primer and Lipgloss. The rest (even contours) are with powder. Lord Knows I spent enough time on my skin care- Garden is well hydrated! Clearly, I got carried Away writing but it’s important I share What I know. Always in hope I read “Only honest” reviews too. Moral of my story: It’s a Process, it’s Not over night and It’s DEFINITELY NOT a one Wo/man Team! (PS- I didnt add Eyecream because if your not already well aware of the MUST HAVE in Eye cream.. We have a LOT more work to do!) But Eye Cream is a Treatment so should be applied after Essence (it also works as a barrier to help avoid other products from getting in our eyes) I won’t bore you with my Tea, Herb, Vitamin & Night regime but it’s a FT job. And TOLB is an EXCELLENT line in my opinion so we can all afford Quality but it’s up to us to hire the staff and be sure, as with any new role, we allow a 90 day probationary period. However, if anyone finds the Overnight Fountain of Youth—- I’m ALL EARS 🌸

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★★★★★ Orden y Estilo en Casa Verified purchase May 29, 2026
Hydrating, Lightweight, and Great for Daily Use

I am very pleased with this hyaluronic acid serum. The lightweight formula absorbs quickly into the skin without feeling sticky or greasy. After using it consistently, my skin felt more hydrated, smooth, and refreshed throughout the day. I also appreciate that it contains Vitamin C and natural ingredients, making it a great addition to my skincare routine. It layers well under moisturizer and makeup and leaves my skin looking healthy and radiant. Overall, this serum provides excellent hydration and feels gentle on the skin. I would definitely recommend it to anyone looking for a quality facial serum for daily use.

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★★★★★ KELLY H. Verified purchase Jun 4, 2026
sooo good!!

i use this every night before bed and have noticed an incredible difference in my skins elasticity. its tighter, firmer and looks incredible. i am 51 and my skin looks better than 10 years ago! the redness is gone. i had rosacea for years. weird blotty red skin and it just was terrible. after using this for a month and its already taken years off my face. its made my skin look so good and tight and healthy that most days i dont even wear foundation. dries quickly and instantly plumps and firms.

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★★★★★ Jemie Verified purchase Jun 5, 2026
Should’ve purchased years ago

Great product, 100% smoothen the texture of your skin, definitely brightens, light wear and not sticky. Buying a second bottle after a couple weeks. One of those products you never want to run out of

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Reviews are from verified Amazon customers, shown for reference. We don't edit or endorse individual reviews.

Tree of Life Retinol Serum with Hyaluronic Acid, 2 Fl Oz: frequently asked questions

Do retinol and hyaluronic acid really work together?

Retinol is one of the most studied actives in skincare, shown to support cell turnover and visibly reduce fine lines and dark spots over consistent use. Hyaluronic acid draws moisture into the skin—useful alongside retinol, which can be drying. The Tree of Life Retinol Serum pairs both in one formula, making it a practical option for targeting wrinkles and dehydration at the same time. Expect gradual results over weeks, not days.

Which is better for older skin, retinol or hyaluronic acid?

They work better together than either does alone. Retinol encourages faster cell turnover—which slows with age—helping to smooth fine lines and fade hyperpigmentation. Hyaluronic acid replenishes surface moisture that retinol can strip away. This serum combines both, making it a sensible pick for mature skin that needs resurfacing and hydration. If you'd prefer to focus purely on hydration, the Tree of Life Hyaluronic Acid Serum is a standalone option.

Should a 60-year-old use retinol?

Yes—retinol is well-suited for mature skin because it targets concerns that deepen with age: fine lines, uneven tone, and dullness. The key is starting slowly. If you're new to retinol, use this serum two or three nights a week and build from there. Some initial flaking or sensitivity is normal; applying it over a light moisturizer can buffer the effect. Always follow with broad-spectrum SPF in the morning.

What should you not mix with retinol?

Avoid using retinol in the same routine as AHAs (glycolic, lactic acid), BHAs (salicylic acid), or benzoyl peroxide—layering these can cause irritation or reduce retinol's effectiveness. Vitamin C is also best saved for a separate morning routine. Use this serum at night on its own, and follow with a gentle, fragrance-free moisturizer to minimize dryness without interfering with the active.

Is Tree of Life a good skincare brand?

Tree of Life is a US-based brand with a following built around straightforward, accessible serums that lead with active ingredients. Their formulas tend to be unfussy—no excessive fillers—which appeals to shoppers who want targeted results without a complicated routine. The Retinol Serum is one of their more consistent sellers, though as with any retinol product, results depend heavily on regular, long-term use rather than brand reputation alone.

Which retinol is best for older skin?

Mature skin often benefits most from a lower-concentration retinol paired with a hydrating ingredient, since sensitivity and dryness tend to increase with age. This Tree of Life serum combines retinol with hyaluronic acid for exactly that reason—it addresses moisture loss while still delivering the resurfacing benefits. A gentler formula used consistently every few nights typically outperforms a high-strength retinol used sporadically.

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